HbA1c can indicate genetic susceptibility to insulin resistance

HbA1c can indicate genetic susceptibility to insulin resistance

HbA1c has long been a monitoring tool for Diabetes Mellitus for several reasons including a pointer to which patients might develop adverse complications (such as acute myocardial infarction, cerebrovascular disease, End Stage Renal Disease, etc.). There might also be an association between variations in HbA1c patterns and genetic susceptibility to insulin deficiency and insulin resistance.

These were some of the points that Dr Kavita Venkatraman, Saw Swee Hock School of Public Health, National University of Singapore, made in a recent presentation in Mumbai. She was speaking at the 9th Annual NGBT (Nextgen Genomics, Biology, Bioinformatics and Technologies) conference being held on 30 September, 2019 to 2nd October,2019. The host of the conference is the SciGenome Research Foundation (SGRF), which is a non-profit organization dedicated to the promotion of science in India.

In another illuminating talk, Professor Shrikant Mane from the Department of Human Genetics, Yale University, New Haven, Connecticut, explained how a genomic approach could be used for tackling a wide range of undiagnosed diseases. Thus he pointed out how de novo mutations in certain chromosomes and certain variable expressive genes could become indicators to the possibility of Congenital Heart Disease. But he also emphasized that despite numerous advances in genomic technologies and medical research over the past decade, more than 30 per cent of the rare diseases remain undiagnosed.

“Over the past nine years NGBT has evolved to create a forum for researchers, students, clinicians, plant and animal scientists, and technology/biology companies from India and across the globe to meet, share and gain knowledge on advances in science and technologies. The science of genomics is revolutionizing healthcare, drug discovery, plant and animal sciences. Our conference is intended to bring these cutting-edge advance accessible to scientist and aspiring students in India,” said Dr Sekar Seshagiri, NGBT Conference Chair and President of SGRF.

Straight Talk

View More