PRO: Challenge of cross-cultural adaptation 

September 11, 2021 0 By Arun Bhatt

Indian clinical investigators may be tempted to use patient-reported outcomes for research. But cultural differences with the west may pose a hurdle 

Patient-Reported Outcomes (PRO) have emerged as an important pillar of assessing health-related quality of life – a multidomain concept that represents the patient’s perception of the effect of illness and treatment on the physical, psychological and social aspects of life. A wide variety of PROs are available for many conditions e.g., SF-36 Health Survey, European Organisation for Research and Treatment of Cancer Questionnaire (EORTC OLQC30) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Although PROs are used extensively by the pharma industry, there is tremendous scope for employing PROs for the evaluation of diverse interventions – surgery, physiotherapy, yoga, alternative therapies etc.

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