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AMR biobanking is the need of the hour

India’s research programme on tackling antimicrobial resistance has just started, with the government announcing that it will set up a biorepository for drug-resistant microbes at National Centre for Microbial Resource (NCMR), Pune. Though India has several biorepositories, a dedicated initiative such as this is the first of its kind. This biobank will be a part […]

Dr Rajani Kanth Vangala
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“We will soon test the world’s first multi-potent innate immune proteins in humans to counter AMR”

Innate immune proteins have been fighting infections in all living organisms for millions of years and bacteria have never been able to develop resistance against them. Despite this well-known fact, no one explored the possibility of leveraging this mechanism to counter one of the worst medical crises in modern times:  antimicrobial resistance (AMR). Now, for […]

C H Unnikrishnan

Artificial intelligence for clinical trials

The successful development of a new drug takes 10-15 years and costs US$1.5-2.0 billion. Clinical trials (CT) consume almost half of the time and cost. Today, high failure rates of CTs are a major obstacle in successful and fast drug development.  Only 10% of new compounds entering the CT phase advance to the regulatory marketing […]

Dr Arun Bhatt

If the doctor’s aim is advancement, he must be very prudent to stick to it

No two people can be equal. Similarly, no two surgeons are equal. One surgeon may possess a ‘sixth sense’ whereas others may have only the five senses to work with. To develop oneself in neurosurgery or any other specialty, the person who is doing it must have a passion to be with the specialty. He […]

Dr P S Ramani

A data-driven approach to mental illness

Clinical translation of genetic loci information from genome-wide association studies into viable models needs a deeper understanding of the underlying molecular and biological processes. This, in turn, requires an integrative effort from clinicians, mental health researchers and those skilled in data science. One of the most interesting aspects of data science is the opportunity to […]

Dr Rajani Kanth Vangala

“India is still about 25 years behind in quality care standards”

Quality care in a hospital is a combination of several standards and practices and not just the medical procedure. While medicine itself is an art that is based on science and clinical evidence, quality care also requires a culture that values not only the patient’s disease, but also his emotional wellbeing as well the confidence […]

CH Unnikrishnan

Clinical research in palliative care: Dilemma and decision

Palliative care is an approach that aims to improve the quality of life (QOL) of patients facing serious problems – physical, psychosocial, and spiritual – associated with life-threatening illness. Palliative care includes a variety of management approaches to provide symptomatic relief of pain and other distressing symptoms, support systems for patients and families to cope, […]

Dr Arun Bhatt